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The quality-control requirements for preliminary tests must be structured so that each analytical run of specimen to be evaluated includes: A urine specimen accredited to consist of no drug; A urine specimen fortified (" spiked") with recognized requirements; Positive controls with a drug or metabolite at or near the threshold or cut-off level.


A minimum of 10 per cent of test samples should be utilized as quality-control samples. The quality-control requirements for confirmatory tests must be structured so that each analytical run of specimen to be confirmed includes: A urine specimen consisting of no drugs; A urine specimen strengthened (" spiked") with recognized standards; A favorable and positive controls with a drug or metabolite at or near the threshold or cut-off level.


Implementation of treatments to guarantee that carry-over does not infect the testing of the private specimen must also be recorded. 7. Review of outcomes ( a) Medical evaluation officer The medical review officer need to be a licensed physician with a knowledge of compound abuse disorders. A positive outcome does not vehicle- matically determine a private as an unlawful drug user.


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In performing his or her responsibilities, the medical evaluation officer need to analyze alternate medical descriptions for a positive test outcome by, for instance, carrying out a medical interview with the individual, examining the individual's case history and figuring out the scientific proof of unlawful usage of any opiate or opium derivatives.


Prior to making a final decision to verify a positive outcome, the medical evaluation officer need to give the individual a chance to talk about the test results with him or her. If the medical review officer determines that there is a genuine medical explanation for the favorable test, the result follows the legal drug usage and no further action need to be taken.


Additionally, based upon the review and examination of reports, quality-control information, multiple samples and other important outcomes, the medical review officer might figure out that the result is scientifically inadequate for further action and declare the test specimen negative. The director of the laboratory need to be readily available to talk to the medical evaluation officer as required.


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( b) Protection of worker records All lab agreements need to need that the contractor comply with the privacy act. In addition, the laboratory agreement should need compliance with the gain access to and confidentiality provisions developed within the jurisdiction where the laboratory practice is maintained. The agreement and the privacy act ought to specifically need that worker records be preserved and utilized with the highest regard for staff member privacy.


8. Certification of laboratory The lab must satisfy all pertinent arrangements and guidelines mentioned in the present paper. In figuring out whether to license a lab or to accept the accreditation, the following criteria ought to be thought about: The adequacy of the laboratory facilities; The competence and experience of the lab personnel; The level of the lab's quality-assurance and quality-control programme; The efficiency of the laboratory on annual performance tests (when in place); The laboratories compliance with the standards as reflected in any laboratory inspection;' Any other aspects impacting there liability and accuracy of drug tests and reporting done by the lab.


Throughout the process, 90 per cent of the number of tests performed should be correctly identified (i.e. recognition and verification of 90 per cent of the overall drug obstacles) or suspension or revocation of the certificate might happen. 00 Thin-layer chromatography 01 M - DNA Testing. A. Huestis, J. E. Henningfield and E.


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Cone, "Blood cannabinoids: absorption.of THC and development of 11-OH-THC and THC-COOH throughout and after cigarette smoking cannabis", Journal of Analytical Toxicology, vol. 16, 1992, pp. 276-282. 02 C. N. Chaing and G. Barnett, "Cannabis result and delta-9-tetrahydrocannabinol plasma level", Medical Pharmacology and Therapies, vol. 36, 1984, pp. 234-238. 03 C. A Dackis and others, "Perseverance of urinary marijuana levels after monitored abstinence", American Journal of Psychiatry, vol.


1196 1198. 04 H. Kalant, "Absorption, diffusion, circulation and elimination of ethanol", Effects of Biological Membranes: The Biology of Alcoholism, B. Kissin and H. Begleiter, eds. (New York, Plum Press, 1971), pp. 1-62. 05 R. C. Baselt, Disposition of Toxic Drugs and Chemicals in Guy, 2nd ed. (Davis, California, Biomedical Publications, 1982), pp.


06 I. Baksaas, "Patterns in drug usage: national and global aspects; antihypertensive drugs", Acta Medica Scandinavica, vol. 683, 1984, pp. 59-66. 07 D. J. King and K. Griffiths, "Patterns in drug utilization: national and worldwide elements; psychedelic drugs 1966-80', Acta Medica Scandinavica, vol. 683, 1984, pp. 71-77. 08 National Transport Security Board, Safety Research Study: Tiredness, Alcohol, Other Drugs, and Medical Consider Fatal-to-the-Driver Heavy Truck Crashes (Vol.


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09 B. M. Kapur, "Patterns of drug usage: a laboratory viewpoint (1987-1992)", unpublished. 10 B. M. Kapur and others, "The incidence of alcohol and drugs among MVA injury admissions to a regional injury system", Procedures of the T 89-11th Worldwide Conference on Alcohol, Drugs and Traffic Security, M.W.D. Perrine, ed.


866-874. 11 G Stoduto and others, "Alcohol and drugs in motor lorry collision admissions to a regional trauma system: group, injury and crash qualities", Proceedings of the 35th Annual Fulfilling of the Association for the Development -of Automotive Medicine, Toronto, 7- 9 October 1991. 12 C. M. Selavka, "Poppy seed streusel.spoils opiate distinction standards", Forensic Urine Drug Screening, September 1991.


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69 (11 April 1988). 14 E. J. Cone and others, "Checking human hair for drugs of abuse- identification of special drug metabolites on hair of drug abusers and examination of decontamination treatments", Journal of Analytical Toxicology, vol. 15, 1991, pp. 250-255. 15 Y. Nakahara, M. Shimamine and K. Takahashi, "Hair analysis for drugs of abuse: movement and stability of methoxyphenamine (as a design compound of methamphetamine) along hair shaft with hair development", Journal of Analytical Toxicology, vol.


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253-257. 16 M. R. Moeller, "Drug detection in hair by chromatographic procedures", Journal of Chromatography, vol. 580, 1992, pp. 125-134. 17 "Society of forensic toxicology advisory committee on analysis of hair for drugs of abuse: modified consensus viewpoint on applicability of hair analysis for drugs of abuse", Tox Talk, vol.


4 (1992 ), p. 3 18 A. W. Jones, "Irregularity of the blood: breath alcohol ratio in vivo", Journal of Research Studies on Alcohol, vol. 39, 1978, pp. 1931-1939. 19 R. N. Harger and others, 'The partition ratio of alcohol in between air and water, urine and blood; estimate and recognition of alcohol in those liquids from analysis of air equilibrated with them", Journal of Biological Chemistry, vol.


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197-213. 20 B. O'Neill, A. F. Williams and K. M. Dubowski, "Variability in blood alcohol concentrations", Journal of Studies on Alcohol, vol. 44, 1983, pp. 222-230. 21 K. M. Dubowski, "Studies in breath-alcohol analysis: biological aspects", Zeitschrift fiir Rechtsmedizin, vol. 76, 1975, pp. 93-117. 22 G (Clinical Lab Testing). Simpson, "Accuracy and.


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32, 1987, pp. 261-268. 23 J. P. Payne, D. W. Hill and N. W. King, "Observations on circulation of alcohol in blood, breath and urine", British Medical Journal, vol. 1, 1966, pp. 196-202. 24 P. Peachey and B. M. Kapur, "Monitoring drinking behaviour with the alcohol dipstick throughout treatment",. Alcohol addiction: Scientific and Experimental Research study, vol.

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